Looking to live it up somewhere between St. Louis and Memphis? Isle Casino Cape Girardeau is calling your name. Here, try your luck at any of more than 850 gaming machines, 20 table games plus 4 live-action poker tables. Enjoy tasty dining options at your choice of 4 fabulous restaurants on site. Enliven your experience with a little live entertainment and extend your visit by taking advantage of great rates at popular local hotels. What are you waiting for?